The report reviews the recent policy developments and activities within the United Nations system to combat trafficking in persons, including the activities of United Nations entities, the Office of the High Commissioner for Human Rights (OHCHR), as well as of the United Nations human rights mechanisms. The report is divided into four chapters. Chapter I presents an overview of the recent developments in the United Nations relating to combating trafficking in persons, bearing in mind global policy developments and the initiatives undertaken by United Nations entities. Chapter II reviews the activities of OHCHR related to combating trafficking in persons. Chapter III presents the Recommended Principles and Guidelines on Human Rights and Human Trafficking. Finally, Chapter IV presents Conclusions.